| 发明名称 |
Spiropiperidine compounds as ligands for ORL-1receptor |
| 摘要 |
A compound of the formula: or a salt, prodrug or solvate thereof, wherein R1 and R2 groups are all hydrogen; A is a benzofuzed azahetero ring; W1-W2 is CH2-CH2; X1-X2 is CH2-CH2; and Z is methylene or carbonyl; or the like, is a ligand for ORL1-receptor and are useful for treating or preventing pain, a CNS disorder or the like in mammalian subjects.
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| 申请公布号 |
US2003078279(A1) |
申请公布日期 |
2003.04.24 |
| 申请号 |
US20020153310 |
申请日期 |
2002.05.22 |
| 申请人 |
PFIZER INC. |
发明人 |
ITO FUMITAKA;KOIKE HIROKI;SUDO MASAKI;YAMAGISHI TATSUYA;ANDO KOJI |
| 分类号 |
C07D491/107;A61K31/438;A61K31/454;A61K31/4545;A61K31/4709;A61K31/496;A61K31/498;A61K31/517;A61K31/537;A61K31/538;A61K31/541;A61K31/55;A61P1/04;A61P1/16;A61P3/04;A61P7/12;A61P11/00;A61P13/12;A61P15/00;A61P25/00;A61P25/02;A61P25/04;A61P25/08;A61P25/16;A61P25/22;A61P25/28;A61P43/00;C07D401/06;C07D401/14;C07D413/06;C07D413/14;C07D417/06;C07D417/14;C07D471/10;C07D491/10;(IPC1-7):A61K31/474;C07D471/12 |
主分类号 |
C07D491/107 |
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