摘要 |
The present invention concerns novel taxane derivatives, their use as antitumor agents, and pharmaceutical formulations.The invention claims compounds of formula I and the use of compounds of formula I or pharmaceutical salts thereof as oral drugs for the treatment of human or veterinary disease.in which:R is phenyl, isopropyl, or tert butyl;R<1 >is -C(O)R<z >in which R<z >is (CH3)3CO-, (CH3)3CCH2-, CH3(CH2)3O-, cyclobutyl-, cyclohexyloxy, or (2-furyl);R<2 >is CH3C(O)O-. |