| 发明名称 |
АНАЛОГИ ТАМАНДАРИНА И ДИДЕМНИНА И СПОСОБЫ ИХ ПОЛУЧЕНИЯ И ПРИМЕНЕНИЯ |
| 摘要 |
The present invention relates to tamandarin and didemnin analogs which have a deoxo-proline residue or a dehydro-proline residue in their structure. These analogs are useful as anti-cancer agents and for other purposes. Methods of making these analogs and methods of using them as inhibitors of protein synthesis, cell growth, and tumorigenesis and as enhancers of apoptosis are also provided. |
| 申请公布号 |
RU2002129885(A) |
申请公布日期 |
2004.03.27 |
| 申请号 |
RU20020129885 |
申请日期 |
2001.04.09 |
| 申请人 |
ДЗЕ ТРАСТИЗ ОФ ДЗЕ ЮНИВЕРСИТИ ОФ ПЕНСИЛЬВАНИЯ (US) |
发明人 |
ЖУЛИ Мадлен М. (US);ЛИАНГ Бо (US);ДИНГ Ксиаобин (US) |
| 分类号 |
A61K38/00;A61P9/10;A61P31/04;A61P31/10;A61P31/12;A61P35/00;A61P37/06;A61P37/08;A61P43/00;C07K5/02;C07K5/083;C07K7/02;C07K11/00 |
主分类号 |
A61K38/00 |
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