发明名称 |
Production scale method of forming microparticles |
摘要 |
The present invention relates to a method for forming microparticles of a material from microdroplets of a solution, wherein the solution comprises the material dissolved in a solvent. The method includes the steps of directing the microdroplets into a freezing zone, wherein the freezing zone is surrounded by a liquified gas, and wherein the microdroplets freeze. The frozen microdroplets are then mixed with a liquid non-solvent, whereby the solvent is extracted into the non-solvent, thereby forming the microparticles.
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申请公布号 |
US6726860(B2) |
申请公布日期 |
2004.04.27 |
申请号 |
US20010006991 |
申请日期 |
2001.12.06 |
申请人 |
ALKERMES CONTROLLED THERAPEUTICS, INC. |
发明人 |
HERBERT PAUL F.;HEALY MICHAEL S. |
分类号 |
B01J2/00;A61K9/16;A61K31/70;A61K38/00;A61K38/21;A61K38/22;A61K38/28;A61K39/395;A61K45/00;A61K47/30;A61K48/00;(IPC1-7):B29B29/02 |
主分类号 |
B01J2/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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