发明名称 |
Flea ecdysone nucleic acid molecules and uses thereof |
摘要 |
The present invention relates to flea ecdysone receptor and ultraspiracle proteins; to flea ecdysone receptor and ultraspiracle nucleic acid molecules, including those that encode such flea ecdysone receptor and ultraspiracle proteins; to antibodies raised against such flea ecdysone receptor and ultraspiracle proteins; and to compounds that inhibit flea ecdysone receptor and/or ultraspiracle activity. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies, and inhibitory compounds. Also included in the present invention are therapeutic compositions comprising a protective compound derived from a protein of the present invention that inhibits the binding between ecdysone receptor and ecdysone as well as the use of such therapeutic compositions to protect animals from flea infestation.
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申请公布号 |
US6767721(B2) |
申请公布日期 |
2004.07.27 |
申请号 |
US20020065200 |
申请日期 |
2002.09.25 |
申请人 |
WISNEWSKI NANCY;BECHER ANNA M.;JARVIS ERIC |
发明人 |
WISNEWSKI NANCY;BECHER ANNA M.;JARVIS ERIC |
分类号 |
C07K14/72;C12N5/02;(IPC1-7):C12P21/06;C12N15/74;C07H21/04;C07K14/00 |
主分类号 |
C07K14/72 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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