摘要 |
This invention provides a process for producing a radioactive arsenic-containing compound, comprising the steps of: (i) subjecting an arsenic-containing compound to a neutron irradiation treatment, said arsenic-containing compound being selected from a group consisting of As2O3, As2S3, As2S2, and a combination thereof, such that the arsenic element contained in the arsenic-containing compound is converted to a radioactive arsenic isotope; and (ii) recovering the resultant product from step (i). This invention also provides a pharmaceutical composition comprising a therapeutically effective amount of the radioactive arsenic-containing compound and a pharmaceutically acceptable carrier. The pharmaceutical composition can be used in the treatment of tumors/cancers such as hematological malignancies and solid tumor.
|
申请人 |
TTY BIOPHARM COMPANY LIMITED;INSTITUTE OF NUCLEAR ENERGY RESEARCH ROCAEC |
发明人 |
CHANG, KWO-PING;CHEN, TE-JUNG;WU, MING-SHIUAN;HUANG, CHUN-YING;LEE, TE-WEI;CHANG, CHIH-HSIEN;CHANG, SHIANG-RONG;KAO, CHARNG-FENG;CHYI, SHYH-YI;HSU, WEI-CHUAN;HSU, YIN-MAO;FU, YING-KAI;FAN, KUO-HSIEN |