Use of intramolecularly, covalently cross-linked proteins as binding partners in immunoassays

摘要

The application discloses the use of intramolecularly, covalently cross-linked DNA polymerase or RNA polymerase proteins as immunological binding partners in immunological test procedures. The protein used may be HIV reverse transcriptase. A method for producing intramolecularly cross-linked HIV reverse transcriptase is also disclosed.