| 发明名称 |
POLYMER-MODIFIED SYNTHETIC PROTEINS. |
| 摘要 |
<p>The present invention relates to methods and compositions for modifying peptides, polypeptides and proteins with polymers, especially glyco-mimetic polymers, so as to improve their biological activity or pharmacokinetic properties. The invention further provides methods and uses for such polymer-modified peptides, polypeptides and proteins. The invention is particularly suitable for use in the synthesis of polymer-modified synthetic bioactive proteins (Figure 1D), and of pharmaceutical compositions that contain such proteins.</p> |
| 申请公布号 |
MXPA03001456(A) |
申请公布日期 |
2004.12.13 |
| 申请号 |
MX2003PA01456 |
申请日期 |
2001.07.12 |
| 申请人 |
GRYPHON THERAPEUTICS, INC. |
发明人 |
WILKEN, JILL, G. |
| 分类号 |
A61K38/00;A61K38/02;A61K38/22;A61K47/34;A61K47/42;A61K47/48;A61P7/00;A61P7/06;A61P9/10;A61P11/02;A61P11/06;A61P17/00;A61P19/02;A61P29/00;A61P31/12;A61P37/06;A61P37/08;A61P43/00;C07K1/00;C07K1/06;C07K14/47;C07K14/505;C07K14/52;C07K17/08;C07K19/00;(IPC1-7):A61K38/02;C07K2/00;C07K14/555;C07K14/54;C07K14/535;C07K14/475;C07K1/13;C07K1/113;A61K38/21;A61K38/20;A61K38/19;A61K38/18 |
主分类号 |
A61K38/00 |
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