发明名称 |
Construction of high efficiency retroviral vector for gene therapy of hunter syndrome |
摘要 |
The present invention provides a retroviral vector containing an iduronate-2-sulfatase (IDS) gene but without selective marker gene, constructed on, as a backbone, a minimum sized MLV-based retroviral vector which does not contain any viral coding sequences but can still produce a high viral titer and drive a high level of gene expression.
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申请公布号 |
US6838280(B2) |
申请公布日期 |
2005.01.04 |
申请号 |
US20030375190 |
申请日期 |
2003.02.25 |
申请人 |
VIROMED LIMITED |
发明人 |
KIM SUNYOUNG;YU SEUNG SHIN;HONG YOUNGTAE;KIM JONG-MOOK;HAN EUN YOUNG |
分类号 |
A61K48/00;C12N15/867;(IPC1-7):C12N15/00;C12N15/86 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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