Apparatus and method for thermal assisted desorption ionization systems

摘要

The present invention is directed to a method and device to desorb an analyte using heat to allow desorption of the analyte molecules, where the desorbed analyte molecules are ionized with ambient temperature ionizing species. In various embodiments of the invention a current is passed through a mesh upon which the analyte molecules are present. The current heats the mesh and results in desorption of the analyte molecules which then interact with gas phase metastable neutral molecules or atoms to form analyte ions characteristic of the analyte molecules.

主权项

1. A device for ionizing an analyte comprising:
one or more mesh; an atmospheric pressure source configured to direct an ionizing species at the one or more mesh; and a supply to generate a pulse of heat to the one or more mesh, where the analyte is present on the one or more mesh.