发明名称 |
Process for preparing 2-cyano-3-hydroxy-N-(phenyl)but-2-enamides |
摘要 |
A process is described for producing 2-cyano-3-hydroxy-N-(phenyl)but-2-enamide, in which a phenyl-substituted 2-cyano-N-(phenyl)acetamide is reacted in the presence of a base, acetic anhydride and at least one solvent, and the resultant 2-cyano-3-hydroxy-N-(phenyl-derivative)but-2-enamide is crystallized by acidification.
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申请公布号 |
US6894184(B2) |
申请公布日期 |
2005.05.17 |
申请号 |
US20040802583 |
申请日期 |
2004.03.17 |
申请人 |
AVENTIS PHARMA DEUTSCHLAND GMBH |
发明人 |
HACHTEL JOCHEN;NEISES BERND;SCHWAB WILFRIED;UTZ ROLAND;ZAHN MARTIN |
分类号 |
A61K31/277;C07C253/30;C07C255/23;(IPC1-7):C07C255/07 |
主分类号 |
A61K31/277 |
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地址 |
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