发明名称 Process for preparing 2-cyano-3-hydroxy-N-(phenyl)but-2-enamides
摘要 A process is described for producing 2-cyano-3-hydroxy-N-(phenyl)but-2-enamide, in which a phenyl-substituted 2-cyano-N-(phenyl)acetamide is reacted in the presence of a base, acetic anhydride and at least one solvent, and the resultant 2-cyano-3-hydroxy-N-(phenyl-derivative)but-2-enamide is crystallized by acidification.
申请公布号 US6894184(B2) 申请公布日期 2005.05.17
申请号 US20040802583 申请日期 2004.03.17
申请人 AVENTIS PHARMA DEUTSCHLAND GMBH 发明人 HACHTEL JOCHEN;NEISES BERND;SCHWAB WILFRIED;UTZ ROLAND;ZAHN MARTIN
分类号 A61K31/277;C07C253/30;C07C255/23;(IPC1-7):C07C255/07 主分类号 A61K31/277
代理机构 代理人
主权项
地址