发明名称 COMPLETE MITOCHONDRIAL GENOME SEQUENCES AS A DIAGNOSTIC TOOLFOR THE HEALTH SCIENCES
摘要 The examination of mutations in the mitochondrial genome is used as a diagnostic system for diseases such as pxostate cancer, and non melanoma skin cancer. Characteristic mutations and rearrangements including, paint mutations (transitions, transversions), deletions, inversions, duplications, recombinations, insertions or combinations thereof in the mitochondrial genome are used as early indicators of prostate cancer, and no n melanoma skin cancer. Moreover, the 4977 bp, or "common deletion" as well as other associated mutations and/or deletions are used as a measure of aging.
申请公布号 CA2450004(A1) 申请公布日期 2005.06.18
申请号 CA20032450004 申请日期 2003.12.18
申请人 1304854 ONTARIO LTD. 发明人 NGOM, ALIOUNE;BIRCH-MACHIN, MARK;THAYER, ROBERT;DAKUBO, GABRIEL D.;TH'NG, JOHN;PARR, RYAN
分类号 G01N33/53;C12M1/00;C12N15/09;C12Q1/68;G01N30/88;G01N33/566;G01N37/00;(IPC1-7):C07H21/00;G06F19/00;G06F17/30;G01N33/574 主分类号 G01N33/53
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