| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a new composition for inhibiting TGF-β (transformation growth factor β). <P>SOLUTION: Inhibitory effects on a rise of the TGF-β in blood and a cerebrospinal fluid are obtained by administering a composition comprising theanine as an active ingredient. Thereby, the new composition for inhibiting the TGF-β can be provided. The composition is useful for prophylactic effects or therapeutic effects based on the TGF-β inhibitory activity for diseases, general fatigue, etc., such as chronic glomerulonephritis, renal interstitial fibrosis, diabetic nephropathy, hepatic fibrosis, hepatocirrhosis, pulmonary fibrosis, keloid, scleroderma, arteriosclerosis, posterior myocardial infarction, cardiac fibrosis, post-vasculogenesis restenosis, acute megakaryoblastic leukemia, adult T-cell leukemia or chronic fatigue. <P>COPYRIGHT: (C)2006,JPO&NCIPI |
