发明名称 COMPOUNDS AND COMPOSITIONS AS c-kit KINASE INHIBITORS
摘要 The invention provides compounds of formulae (Ia) and (IIa), wherein the radical meanings are defined in the claims, and pharmaceutical compositions thereof, which are useful as protein kinase inhibitors, as well as methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated kinase activity. In some embodiments, the invention provides methods for using such compounds to treat, ameliorate or prevent diseases or disorders that involve abnormal activation of c-kit or c-kit and PDGFR (PDGFRα, PDGFRβ) kinases.
申请公布号 EA024293(B1) 申请公布日期 2016.09.30
申请号 EA20140090540 申请日期 2012.08.28
申请人 NOVARTIS AG 发明人 YEH VINCE;LI XIAOLIN;LIU XIAODONG;LOREN JON;MOLTENI VALENTINA;NABAKKA JULIET;NGUYEN BAO;PETRASSI HANK, MICHAEL, JAMES
分类号 C07D471/04;A61K31/437;A61P3/00;A61P11/00;A61P17/00;A61P29/00 主分类号 C07D471/04
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