发明名称 Carboxylic acid compounds and medicinal compositions containing the same as the active ingredient
摘要 Disclosed are compounds represented by the general formula (I), wherein each symbol is as defined in the specification. The compounds bind specifically to DP receptors and antagonize the same, but only weakly bind to other prostaglandin receptors, enabling the production of drugs having few side effects. They are useful in preventing and/or treating allergic diseases including allergic nephritis, allergic conjunctivitis, atopic dermatitis, bronchial asthma, food allergies; systemic mast cell disease; systemic mast cell activation disorder; anaphylactic shock; airway contraction; urticaria; eczema; diseases associated with itching including atopic dermatitis; inflammation; chronic obstructive pulmonary disease, ischemic reperfusion injury; cerebrovascular disorders; rheumatoid arthritis; pleuritis and ulcerative colitis.
申请公布号 NZ545934(A) 申请公布日期 2009.05.31
申请号 NZ20040545934 申请日期 2004.09.16
申请人 ONO PHARMACEUTICAL CO., LTD. 发明人 NAGANAWA, ATSUSHI;IWAHASHI, MAKI;KINOSHITA, ATSUSHI;SHIMABUKURO, ATSUSHI;OGAWA, SEIJI;YANO, KOJI;OKADA, YUTAKA;TSUKAMOTO, KOHKI;MATSUNAGA, YOKO;NAMBU, FUMIO;KOBAYASHI, KAORU;KISHIDA, YOKO;KAWAUCHI, SHOUJI
分类号 A61K31/343;A61K31/538;A61P1/04;A61P1/14;A61P1/16;A61P3/04;A61P7/02;A61P9/10;A61P11/00;A61P11/02;A61P13/10;A61P17/04;A61P17/10;A61P19/02;A61P21/00;A61P25/00;A61P25/06;A61P25/20;A61P29/00;A61P37/06;A61P37/08;A61P43/00;C07D265/36;(IPC1-7):C07D265/36;C07D307/80;C07D319/20;C07D317/46 主分类号 A61K31/343
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