发明名称 |
PROCEDIMIENTO PARA LA PREPARACION DE 1-(2-CIANO-5-METILFE- NIXI) - 2 - HIDROXI-3-ALCOHILOINFERIOR-AMINOPROPANOSRECEMI- COS U OPTICAMENTE ACTIVOS Y SUS SALES POR ADICION DE ACIDO. |
摘要 |
<p>1-(2-Cyano-5-methylphenoxy)-2-hydroxy-3-alkylaminopropanes. (I):- (where R is 2-6C alkyl, pref. t. butyl are used for treating coronary conditions, tachycardia and hypertonia. They are prepd. e.g. from an epoxypropane or halohydrin and NH2R or RNHCONHR or by introducing the alkyl into the unsubstd. amine or by removing an easily hydrolysable gp. G from -OCH2 HCH2NHR or by removing protective gp. P from -OCH2 HCH2 R or by hydrolysing an oxazolidinone or by diazotising an 2-aminomethylphenoxy cpd. to the 2-cyano- cpd.</p> |
申请公布号 |
ES391134(A1) |
申请公布日期 |
1973.07.16 |
申请号 |
ES19340003911 |
申请日期 |
1971.05.13 |
申请人 |
C. H. BOEHRINGER SOHN |
发明人 |
|
分类号 |
C07C213/04;A61K31/275;C07C67/00;C07C217/32;C07C217/34;C07C253/00;C07C255/30;C07C255/53;C07C255/54;E05D15/44;E06B3/32;(IPC1-7):07C/;61K/ |
主分类号 |
C07C213/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|