摘要 |
<p>1,266,670. Dibenzothiepin derivatives. SPOFA UNITED PHARMACEUTICAL WORKS. 23 Oct., 1970 [25 Oct., 1969], No. 50384/70. Heading C2C. Novel compounds of Formula I (in which R<SP>1</SP> is H, halogen, CF 3 , C 1-4 alkyl, C 1-4 alkoxy or C 1-4 alkylthio, and R<SP>2</SP> is CN, COOH, COOR<SP>3</SP>, CONR<SP>4</SP>R<SP>5</SP> or COR<SP>6</SP>, where R<SP>3</SP> is C 1-4 alkyl, each of R<SP>4</SP> and R<SP>5</SP> is H or C 1-4 alkyl, and R<SP>6</SP> is C 1-4 alkyl or phenyl) and their acid addition salts, are prepared by reacting a compound of Formula II with a compound of formula CH 2 =CH-R<SP>2</SP> and, if desired, converting the product into an acid addition salt. The novel compounds and salts have neuroleptic activity.</p> |