发明名称 PROCEDIMIENTO DE PREPARACION DE NUEVAS 10-PIPERAZINO-10,11-DIHIDROBIBENZONB,FNTIEPINAS.
摘要 <p>1,266,670. Dibenzothiepin derivatives. SPOFA UNITED PHARMACEUTICAL WORKS. 23 Oct., 1970 [25 Oct., 1969], No. 50384/70. Heading C2C. Novel compounds of Formula I (in which R<SP>1</SP> is H, halogen, CF 3 , C 1-4 alkyl, C 1-4 alkoxy or C 1-4 alkylthio, and R<SP>2</SP> is CN, COOH, COOR<SP>3</SP>, CONR<SP>4</SP>R<SP>5</SP> or COR<SP>6</SP>, where R<SP>3</SP> is C 1-4 alkyl, each of R<SP>4</SP> and R<SP>5</SP> is H or C 1-4 alkyl, and R<SP>6</SP> is C 1-4 alkyl or phenyl) and their acid addition salts, are prepared by reacting a compound of Formula II with a compound of formula CH 2 =CH-R<SP>2</SP> and, if desired, converting the product into an acid addition salt. The novel compounds and salts have neuroleptic activity.</p>
申请公布号 ES384866(A1) 申请公布日期 1973.07.16
申请号 ES19660003848 申请日期 1970.10.24
申请人 SPOFA, SPOJENE PODNIKY PRO ZDRAVOTNICKOU VYROBU 发明人
分类号 C07D337/14;C07D409/04;(IPC1-7):07D/;61K/ 主分类号 C07D337/14
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