摘要 |
Compounds of the formula WHEREIN R is alkyl having 2 or 3 carbon atoms, alkyl having 2 or 3 carbon atoms substituted by one or more hydroxyl and dialkylamino wherein the latter alkyl has 1 to 4 carbon atoms, alkenyl containing up to 3 carbon atoms or cycloalkyl containing up to 6 carbon atoms. The compounds are prepared by reacting 2-methyl-3-ethoxycarbonyl-5-hydroxy indole with a primary amine of the formula RNH2 in an excess of formol. The compounds possess analgesic, antiinflammatory, spasmolytic, vasodilatatory, hypotensive, diuretic and respiratory analeptic properties. |