STABILIZED LIQUID AND LYOPHILIZED ADAMTS13 FORMULATIONS

摘要

The present invention relates to a stabilized formulation of ADAMTS13 protein for treating or preventing a disease or condition associated with an ADAMTS13 or von Willebrand factor (VWF) dysfunction. Also provided is a lyophilized formulation of ADAMTS13. Furthermore, provided are a method for manufacturing the stabilized ADAMTS13 formulation, a kit comprising said formulation and a method of treating and preventing a disease or condition associated with a VWF or ADAMTS13 dysfunction.