| 摘要 |
1459121 Coating process ZENYAKU KOGYO KK 27 Feb 1974 [27 Feb 1973 13 March 1973 (3)] 8952/74 Heading A5B [Also in Division B2] Solid particles such as granules, pills or tablets are coated with a film of digestive-tractsoluble material by a process which comprises adjusting, if necessary, the water content of the particles to 15 to 30% by weight of the particles, adding an organic solvent solution of the digestive-tract-soluble material, and drying the particles whilst submitting them to a rolling movement. The rolling movement may be. provided by a rotary disc rotating at a peripheral speed of between 200 and 450 metres/minute. The solvents may be a mixture of C 1 -C 3 alcohols C 1 or C 2 halogenated hydrocarbons and C 3 or C 4 ketones. The digestivetract-soluble material may be a dialkylaminoethyl methacrylate-alkyl methacrylate, alkyl vinylpyridine-methacrylic acid-alkyl acrylate, or alkyl methacrylate-metlhacrylic acid copolymer, a polyvinylacetal dialkylaminoacetate, or a dicarboxylic acid half ester of cellulose acetate. Water may be added during the addition of the solution, to prevent the particles sticking together.
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