| 摘要 |
<p>Phenoxypropylamine derivatives of the general formula: R NH-CO-N ANGLE R1 (1) O-CH2-CH-CH2-NH-R3 ¦ OH in which R is a hydrogen atom or a straight-chain or branched alkyl group containing up to 10 carbon atoms, R1 is a hydrogen atom, a straight-chain or branched alkyl group containing up to 10 carbon atoms or a cyclopentyl, cyclohexyl, benzyl or phenyl group or R and R1 taken together form a pentamethylene-(1,5), tetramethylene-(1,4), 2-azapentamethylene-(1,5), 3-azapentamethylene-(1,5) or 3-oxapentamethylene-(1,5)-group, R2 is a hydrogen atom or an alkyl group containing up to 6 carbon atoms or a benzyl or phenyl group, R3 is a branched alkyl group containing 3 to 6 carbon atoms, a cyanoalkyl group containing up to 6 carbon atoms or a cycloalkyl group containing 3 to 7 carbon atoms and R4 is a hydrogen atom, an alkyl group containing up to 6 carbon atoms or a benzyl group, and the pharmaceutically-acceptable salts thereof having a cardioselective beta -blocking action.</p> |
