发明名称 |
PHARMACOLOGICALLY ACTIVE COMPOUNDS |
摘要 |
A process for the production of compounds having activity as histamine H2-receptor antagonists and having the formula where Y is a lower alkyl group, and pharmaceutically acceptable acid addition salts thereof, in which 4-hydroxy-methyl-5-(2-aminoethyl)thiomethylimidazole is reacted with a dilower alkyl dithioiminocarbonate which is subsequently reacted with an amine of formula YNH2. The salts can be prepared by known methods. |
申请公布号 |
ZA7603686(B) |
申请公布日期 |
1977.05.25 |
申请号 |
ZA19760003686 |
申请日期 |
1976.06.21 |
申请人 |
SMITH KLINE & FRENCH LABORATORIES LTD |
发明人 |
WHITE G |
分类号 |
C07D233/66;A61K31/4164;A61K31/44;A61K31/4427;A61P43/00;C07D233/54;C07D233/64;C07D233/90;C07D401/12 |
主分类号 |
C07D233/66 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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