| 摘要 |
This invention provides new compounds of formula I, <IMAGE> I wherein R is alkyl of 3 to 7 carbon atoms or cycloalkyl of 3 to 7 carbon atoms, cycloalkyl of 3 to 7 carbon atoms monosubstituted by alkyl of 1 to 4 carbon atoms, alpha -dialkylpropynyl of 5 to 9 carbon atoms or alpha -dialkyl-allyl of 5 to 9 carbon atoms, hydroxyalkyl of 2 to 7 carbon atoms or phenoxyalkyl of 8 to 11 carbon atoms, the oxygen atom of the last two radicals being separated by at least two carbon atoms from the nitrogen atom to which R is bound, R1 is I. HYDROGEN OR ALKYL OF 1 TO 4 CARBON ATOMS IN THE 2,3,6 OR 7 POSITION, OR II. CHLORINE OR BROMINE, IN THE 2, 3 OR 7 POSITION, III. NITRO OR -NHA wherein A is alkanoyl of 1 to 4 carbon atoms, in the 2, 3 or 7 position, or IV. FLUORINE, CYANO OR COOB, wherein B is alkyl of 1 to 4 carbon atoms, in the 2 or 3 position, and R2 is I. HYDROGEN OR ALKYL OF 1 TO 4 CARBON ATOMS IN THE 2, 3, 6 OR 7 POSITION, II. CHLORINE OR BROMINE, IN THE 2, 3 OR 7 POSITION, OR III. FLUORINE IN THE 2 OR 3 POSITION, USEFUL IN THE TREATMENT OF HEART DISEASES.
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