| 摘要 |
Polypeptides of the formula I wherein A is L- or D-Trp, X is H-(Aeg)m-Cys- or H-(Aeg)m-Ala-Gly-Cys-, Y is -Cys-(Aeg)n-OH or X and Y taken together are a 2-aminoethyl-glycyl group in the ring position and m and n are 0, 1, 2, 3 or 4, provided that m + n are at least 1, the cyclic disulfide derivatives, protamine zinc and protamine aluminum complexes and pharmaceutically acceptable acid addition salts thereof, having valuable pharmacological properties, and methods for the preparation thereof using conventional liquid or solid phase syntheses. |
