发明名称 |
COMPOSITIONS FOR TREATING AND/OR DIAGNOSING COLON CANCER, AND APPLICATIONS THEREOF |
摘要 |
PROBLEM TO BE SOLVED: To provide techniques for treating and/or diagnosing colon cancer having mutant KRAS and mutant BRAF.SOLUTION: Colon cancer is treated with a composition containing miR-31 inhibitor. The diagnosis is performed based on the expression level of miR-31 in the biological sample derived from a patient with colon cancer. The colon cancer cells containing miR-31 or the mimic of miR-31 are produced, and drugs for treating colon cancer are screened using the colon cancer cells.SELECTED DRAWING: None |
申请公布号 |
JP2016169158(A) |
申请公布日期 |
2016.09.23 |
申请号 |
JP20130126021 |
申请日期 |
2013.06.14 |
申请人 |
SAPPORO MEDICAL UNIV |
发明人 |
NOSEI KATSUHIKO;SUZUKI HIROSHI;YAMAMOTO HIROYUKI;SHINOMURA YUKIHISA |
分类号 |
A61K45/00;A61K31/7088;A61K31/713;A61K39/395;A61P1/00;A61P35/00;A61P43/00;C12Q1/68;G01N33/15;G01N33/50 |
主分类号 |
A61K45/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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