| 发明名称 |
METHODS OF TREATING PRURITUS |
| 摘要 |
A method of treating pruritus (itching) in a subject in need thereof is carried out by administering the subject an active agent in a treatment effective amount, wherein the active agent is a superoxide dismuate (SOD) mimetic. The SOD mimetic can be a complex of a metal (e.g., manganese) and an organic ligand, with suitable organic ligands including porphyrins, polyamines, salens, nitroxides, and fullerenes. Compositions for carrying out such methods are also described. |
| 申请公布号 |
US2016324868(A1) |
申请公布日期 |
2016.11.10 |
| 申请号 |
US201515109164 |
申请日期 |
2015.01.21 |
| 申请人 |
DUKE UNIVERSITY ;BIOMIMETIX JV, LLC |
发明人 |
Ji Ru-Rong;Liu Tong;Batinic-Haberle Ines;Warner David S.;Stone Kimberly C.;Crapo James D. |
| 分类号 |
A61K31/555;A61K9/00 |
主分类号 |
A61K31/555 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of treating pruritus (itching) in a subject in need thereof, comprising administering said subject an active agent in a treatment effective amount, wherein said active agent is a superoxide dismuate (SOD) mimetic. |
| 地址 |
Durham NC US |
