| 摘要 |
Compounds of the formula below are useful for expanding the lumina of air passages in a mammal in need of said treatment. The compounds are also useful for treating atopic eczema and urticaria. <IMAGE> wherein X and Y are the same or different and are hydrogen, fluoro, chloro, bromo, nitro, trifluoromethyl, alkyl of one to four carbon atoms, inclusive, alkoxy of one to four carbon atoms, inclusive, and cyano; R1 is hydrogen, methyl or ethyl; R2 is hydrogen, alkyl of one to six carbon atoms, inclusive, phenyl, benzyl, CH2Z wherein Z is fluoro, chloro, or bromo, CO2M, CH2CO2M, CH2CH2CO2M and CHR3CO2M wherein M is hydrogen, alkyl of one to four carbon atoms, inclusive, or a physiologically acceptable metal or amine cation and R is alkyl of one to three carbon atoms, inclusive, with the proviso that M is not hydrogen when R2 is CH2CO2M or CHR3CO2M.
|
