1-Piperidine-alkylene ketones, pharmaceutical compositions thereof and method of use thereof

摘要

Pharmaceutically useful compounds of the following formula: wherein R1 represents hydrogen or hydroxy; R2 represents hydrogen; or R1 and R2 taken together form a second bond between the carbon atoms bearing R1 and R2; n is a positive whole integer of from 1 to 5; R3 is -CH3, -CH2OH, -COOH or -COOalkyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched; and A and B are individually hydrogen or hydroxy; with the provisos that at least one of A or B is hydrogen and one of A or B is other than hydrogen when R3 is -CH3; and pharmaceutically acceptable acid addition salts thereof.