| 发明名称 | Single-domain antibodies that bind to HIV-1 Nef with high affinity | ||
| 摘要 | The invention relates to antibody fragments with simple heavy chain or sdAbs, characterized in that they consist of anti HIV Nef-protein fragments corresponding to all or a portion of the HHV domains of camelids, particularly llamas. | ||
| 申请公布号 | US9512203(B2) | 申请公布日期 | 2016.12.06 |
| 申请号 | US200812734773 | 申请日期 | 2008.11.18 |
| 申请人 | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) | 发明人 | Baty Daniel;Chartier Martine Jeanne Pierrette;Chames Patrick;Benichou Serge Salomon;Ciogullari Stephane Eric;Bouchet Jerome Christophe Marie Abel |
| 分类号 | C07K16/10;C12N15/00;A61K39/42;C07K16/00 | 主分类号 | C07K16/10 |
| 代理机构 | Young & Thompson | 代理人 | Young & Thompson |
| 主权项 | 1. A single-domain antibody (sdAb), comprising the amino acid sequence selected from the group consisting of SEQ ID NO: 7 to SEQ ID NO: 12. | ||
| 地址 | Paris FR | ||