PROCEDEU PENTRU PREPARAREA UNOR CIS-BICICLOOCTILAMINE

摘要

A process for preparing antidepresssant 2-phenylbicyclooctylamines of formula (I): (I) where R1 and R2 represent C1-3 alkyl and Ar represents a phenyl group optionally substituted by up to two halogen atoms, by reduction of a novel enamine intermediate of formula: (II) where R3 and R4 are hydrogen or taken together represent a single bond and where X is hydrogen, bromine or chlorine.