3,7-Disubstituted-2 or 3-cephem-4-carboxylic acid compounds

摘要

3,7-Disubstituted-2 or 3-cephem-4-carboxylic acid compounds of the formula: <IMAGE> wherein R1 is acylamino or ar(lower)alkylamino; R2 is carboxy or carboxy protected by a pharmaceutically acceptable group; -N-R3, R4 is di(lower)alkylamino(lower)alkylamino, an unsaturated or saturated 3 to 8 membered heteromonocyclic (lower)alkylamino group containing 1 to 4 nitrogen atoms, an unsaturated or saturated 3 to 8 membered heteromonocyclic (lower)alkylamino group containing 1 to 4 nitrogen atoms substituted by lower alkyl or hydroxy(lower) alkyl, an unsaturated or saturated 5 to 6 membered heteromonocyclic group containing 2 to 4 nitrogen atoms, an unsaturated or saturated 5 to 6 membered heteromonocyclic group containing 2 to 4 nitrogen atoms substituted by lower alkyl or hydroxy(lower)alkyl or hydroxypiperidino, and X is -S- or <IMAGE> and pharmaceutically acceptable salts thereof. The present compounds are useful for the treatment of infectious diseases in animals and human beings.