发明名称 |
FORFARANDE FOR FRAMSTELLNING AV 5-FLOURURACILDERIVAT |
摘要 |
A new and industrially useful method of producing 1(or 1,3-bis)-(tetrahydro-2-furyl)-5-fluorouracil or a mixture thereof by reacting 5-fluorouracil with 2,3-dihydrofuran at elevated temperature in a closed vessel. Depending upon reaction conditions, each of the above 5-fluorouracil derivatives or a mixture of them is produced. 1,3-Bis-(tetrahydro-2-furyl)-5-fluorouracil thus formed can be converted to 1-(tetrahydro-2-furyl)-5-fluorouracil by solvolysis under non-acidic conditions. |
申请公布号 |
SE423389(B) |
申请公布日期 |
1982.05.03 |
申请号 |
SE19760013305 |
申请日期 |
1976.11.26 |
申请人 |
* TAKEDA CHEMICAL INDUSTRIES LTD |
发明人 |
I * MINAMI;Y * YOSHIOKA;H * NOMURA |
分类号 |
C07D405/14;(IPC1-7):07D405/04 |
主分类号 |
C07D405/14 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|