| 发明名称 | Latex particles for agglutination assay | ||
| 摘要 | A latex particle for high-sensitive agglutination assay and a reagent for agglutination assay including the particle are provided. The latex particle barely initiates non-specific reactions and can readily prepare diagnostic agents. A latex particle for agglutination assay including a polymerizable monomer having a phenyl group, a polymerizable monomer having a phenyl group and a salt of sulfonic acid, and a polymerizable monomer represented by Formula (1): CH2═CR1—COO(CH2CH2O)n—R2 (1) where R1 represents a hydrogen atom or a methyl group; R2 represents a hydrogen atom or a methyl group; and n is 1≦n<20, wherein the density of functional groups derived from the polymerizable monomer represented by Formula (1) on the surface of the particle is 0.05 to 0.5 μmol/m2. | ||
| 申请公布号 | US9465033(B2) | 申请公布日期 | 2016.10.11 |
| 申请号 | US201314389182 | 申请日期 | 2013.04.01 |
| 申请人 | SEKISUI MEDICAL CO., LTD. | 发明人 | Kitahara Shinichiro;Takahashi Yuki |
| 分类号 | G01N33/545;C08L33/14;G01N33/58;C08F212/08;C08F212/14;C08F220/28 | 主分类号 | G01N33/545 |
| 代理机构 | Birch, Stewart, Kolasch & Birch, LLP | 代理人 | Birch, Stewart, Kolasch & Birch, LLP |
| 主权项 | 1. A latex particle for agglutination assay, comprising: a polymerizable monomer having a phenyl group, a polymerizable monomer having a phenyl group and a salt of sulfonic acid, and a polymerizable monomer represented by Formula (1): CH2═CR1—COO(CH2CH2O)n—R2 (1)where R1 represents a hydrogen atom or a methyl group; R2 represents a hydrogen atom or a methyl group; and n is 1≦n<20, wherein the density of functional groups derived from the polymerizable monomer represented by Formula (1) on the surface of the particle is 0.05 to 0.5 μmol/m2. | ||
| 地址 | Tokyo JP | ||