| 发明名称 |
Methods for the preparation of diasteromerically pure phosphoramidate prodrugs |
| 摘要 |
Provided are methods and intermediates for preparing diastereomerically pure phosphoramidate prodrugs of nucleosides of Formulas Ia and Ib:;
The compounds of Formula Ia and Ib are useful for the treatment Hepatitis C infections. |
| 申请公布号 |
US9487544(B2) |
申请公布日期 |
2016.11.08 |
| 申请号 |
US201514746430 |
申请日期 |
2015.06.22 |
| 申请人 |
Gilead Sciences, Inc. |
发明人 |
Cho Aesop;Clarke Michael O'Neil Hanrahan;Wolckenhauer Scott Alan |
| 分类号 |
C07H21/00;C07F9/24;A61K31/7052;A61K31/7042;C07H1/00;C07H19/02;C07H19/10;C07H19/20;C07F9/6558;C07F9/6561 |
主分类号 |
C07H21/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A compound selected from the group consisting of |
| 地址 |
Foster City CA US |
