发明名称 AQUEOUS SUSPENSION AGENT COMPRISING GLUCOCORTICOSTEROID NANOPARTICLES
摘要 [Problem] To provide an aqueous suspension comprising a glucocorticosteroid compound as an active ingredient. More particularly, to provide a practically usable medicinal composition that comprises a glucocorticosteroid compound as an active ingredient. [Solution] An aqueous suspension agent characterized by comprising nanoparticles of a glucocorticosteroid compound and a dispersion stabilizing agent; the aqueous suspension agent wherein the average particle diameter of the nanoparticles is 300 nm or less and the D90 particle diameter thereof is 450 nm or less; and a medicinal composition for parenteral administration, an injection, eye drops or ear drops comprising the aforesaid aqueous suspension, more particularly, eye drops for treating or preventing an inflammatory eye disease, or ear drops for treating or preventing an inflammatory ear disease.
申请公布号 WO2016181935(A1) 申请公布日期 2016.11.17
申请号 WO2016JP63752 申请日期 2016.05.09
申请人 ACTIVUS PHARMA CO., LTD. 发明人 TADA Takahiro;KAGAMI Kazuhiro;YOKOTA Shiro;KIKUCHI Kenta
分类号 A61K31/57;A61K9/10;A61K31/573;A61K31/58;A61K47/10;A61K47/12;A61K47/24;A61K47/32;A61K47/34;A61K47/38;A61P29/00;A61P31/04 主分类号 A61K31/57
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