| 发明名称 | Crystalline form of vortioxetine hydrobromide | ||
| 摘要 | The present invention is directed to a crystalline compound comprising a hydrobromide acid (HBr) salt of a compound of formula (I) (1-{2-[(2,4-dimethylphenyl)sulfanyl]phenyl}piperazine, INN: vortioxetine), having an XRPD pattern with characteristic peaks (expressed in 2θ±0.2° 2θ (CuKα radiation)) at 5.5°, 14.8°, 16.7° and 20.0° and processes for obtaining the same.; | ||
| 申请公布号 | US9499504(B2) | 申请公布日期 | 2016.11.22 |
| 申请号 | US201314429388 | 申请日期 | 2013.09.18 |
| 申请人 | Sandoz AG | 发明人 | Hotter Andreas;Enders Michael;Griesser Ulrich |
| 分类号 | C07D295/096;A61K31/495 | 主分类号 | C07D295/096 |
| 代理机构 | Luedeka Neely Group, P.C. | 代理人 | Luedeka Neely Group, P.C. |
| 主权项 | 1. A crystalline compound comprising a hydrobromic acid (HBr) salt of a compound of formula I (1-{2-[(2,4-dimethylphenyl) sulfanyl]phenyl}piperazine)-{2-[(2,4-dimethylphenyl)-sulfanyl]phenyl}piperazine),having an XRPD pattern with characteristic peaks (expressed in 2θ±0.2° 2θ (CuKα radiation)) at 5.5°, 14.8°, 16.7° and 20.0°. | ||
| 地址 | CH | ||