CONTRACEPTIVE VAGINAL TABLETS AND MANUFACTURING METHOD THEREOF

摘要

The composition of the tablets is as follows: 0.2 to 3 parts by weight of boric acid, 10 to 20 parts by weight of tartaric acid, 1 to 2 parts by weight of derivatives of sodium bisulphite and of vitamin K3, 0.8 to 1.2 parts by weight of polyvinylpyrrolidone, 2 to 5 parts by weight of magnesium stearate, 8 to 12 parts by weight of carboxymethylcellulose, 15 to 65 parts by weight of microcrystalline cellulose. The vaginal tablets contain preferably from 5 to 10 mg of derivatives of sodium bisulphite and of vitamin K3, and their total weight is 500 mg. Preferably said tablets are produced by separately homogenizing the boric acid, the tartaric acid and the derivative of sodium bisulphite and of vitamin K3, as well as the polyvinylpyrrolidone, the magnesium stearate, the carboxymethylcellulose, the lactose and the microcrystalline cellulose so as to obtain pulverulent mixtures, and by mixing the pulverulent mixtures obtained and compressing them to form the tablets. Ten minutes before the sexual intercourse, the tablets should be introduced to the bottom of the fornix vaginae after having moistened the tablets with water.