CELL LINES FOR SCREENING ODORANT AND AROMA RECEPTORS
摘要
Provided herein is a cell line with improved odorant receptor function comprising an activated endogenous RTP1 gene, which further expresses an RTP1 protein. Further provided herein is a method for specifically activating an endogenous RTP1 gene in a eukaryotic cell using a CRISPR/Cas9 derived technique. Also provided herein is a method for identifying compounds with desired effects such as perfume or aroma modulators in said cell line.
申请公布号
WO2016201153(A1)
申请公布日期
2016.12.15
申请号
WO2016US36777
申请日期
2016.06.09
申请人
FIRMENICH SA;JEONG, Hyo-Young;PFISTER, Patrick;ROGERS, Matthew