| 摘要 |
Title compds. I (M=H, Na) were prepd. Thus, 1.3g 2-(2-aminothiazol-4-yl)-methoxy- aminoacetate in 10mL ethyl acetate was treated with 0.76mL phosphorooxychloride and 0.5mL N,N-dimethylacetamide to give its said choloride (A). 2.2g 7-amino-3-(1-methyl -1H-tetrazol-5-yl)-thiomethyl-3-cepham carboxylic acid was dissolved in H2O/acetone (20mL/10mL) and reacted with A at pH=6.5 for 2hrs. to give 2.77g 7-2-(2-aminothiazol-4-yl)-2-methoxyiminoacetamido-3-(1-methyl-1H-tetrazol-4-yl)-thio- methyl -3-cepham-4-carboxylic acid
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