发明名称 Oral product for controlling gingivitis
摘要 An oral composition for treating gingivitis and periodontitis comprising an oral vehicle and an effective amount of the water insoluble antigingivitis agent, imidazolyl-1-1-(p-chlorophenoxy) 3-3-dimethyl 2-butanone solubilized in a nonionic compound containing a mixture of hydrophobic and hydrophilic groups of sufficient length to effect solubilization in an aqueous vehicle, in the weight ratio of 1:1 to 25:1 and preferably 3:1 to 25:1 solubilizer:imidazoyl compound, said agent being selectively effective against the gram negative anaerobic micro-organisms associated with periodontitis.
申请公布号 US4514382(A) 申请公布日期 1985.04.30
申请号 US19840570446 申请日期 1984.01.16
申请人 COLGATE-PALMOLIVE COMPANY 发明人 GAFFAR, ABDUL;DAVIS, CALVIN B.;VASERS, MARGITA L.
分类号 A61K8/49;A61Q11/00;(IPC1-7):A61K7/22;A61K7/16 主分类号 A61K8/49
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