发明名称 CRUSH-RESISTANT SOLID ORAL DOSAGE FORM
摘要 The present invention relates to a method of imparting crush-resistance to an oral solid dosage form comprising a drug prone to abuse, so as to prevent the unintended and illicit use of the dosage form.
申请公布号 US2016310418(A1) 申请公布日期 2016.10.27
申请号 US201415103570 申请日期 2014.12.09
申请人 SUN PHARMACEUTICAL INDUSTRIES LIMITED 发明人 FANDA Anuj Kumar;VIVEK Kumaravel;SHARMA Ravesh Kumar;GARG Vinay Kumar;SINGH Romi Barat
分类号 A61K9/68;A61K31/138;A61K9/20;A61K9/28;A61K47/34;A61K9/48 主分类号 A61K9/68
代理机构 代理人
主权项 1. A crush-resistant oral solid dosage form, comprising: a) a therapeutically effective amount of a drug prone to abuse; and b) a chewing gum base comprising a chewable plastic polymer,wherein the amount of said gum base is such that it causes the dosage form to deform plastically without breaking into powder when said dosage form is tampered with for abuse.
地址 Mumbai, Maharashtra IN