PEPTIDES INCLUDING BINDING DOMAIN OF PLASMODIUM FALCIPARUM PROTEINS (CBP1 AND CBP2) TO CHEMOKINE CX3CL1

摘要

The invention relate to isolated peptides including binding domain of the Plasmodium Falciparum proteins (CBP1 and CBP2) to the chemokine CX3CL1 which has the property to inhibit the cytoadherence of infected red blood cells (iRBC) to endothelial cells. These isolated peptides (or their specific antibody) are used for the prevention or the treatment of Malaria and also acting as "CX3CL1 binding protein" for the treatment of inflammatory diseases or CX3CL1 -associated disease.