发明名称 Storage of red blood cells
摘要 Use of compounds of formula (I) <IMAGE> (I) to provide a more effective delivery of oxygen to the tissues of a mammalian, including human, recipient. In vivo applications include the relief or amelioration of conditions wherein there is tissue hypoxia; in vitro the compounds are of use in the storage of mammalian, including human, red blood cells to maintain their oxygen-delivery capacity and prolong their useful storage life. Also provided is a sterile, sealed vessel containing an anticoagulant, a non-toxic amount of a compound of formula (I) and optionally mammalian, in particular human, red blood cells.
申请公布号 US4626431(A) 申请公布日期 1986.12.02
申请号 US19840662709 申请日期 1984.10.19
申请人 BURROUGHS WELLCOME CO. 发明人 BATCHELOR, JOHN F.;HYDE, RICHARD M.;LIVINGSTONE, DAVID J.
分类号 C07D311/28;A61K31/35;A61K31/352;A61P7/00;C07D311/86;(IPC1-7):A61K35/18;A01N1/02 主分类号 C07D311/28
代理机构 代理人
主权项
地址