发明名称 |
METHOD FOR PREDICTION OF RISK OF POAG WITH INEFFECTIVE LOCAL HYPOTENSIVE THERAPY |
摘要 |
FIELD: medicine.SUBSTANCE: invention aims at predicting risk of developing primary open-angle glaucoma (POAG) with ineffective local antihypertensive therapy. DNA is extracted from peripheral venous blood of Russian natives of Central Black Earth Region and polymorphisms are analysed VEGF-A c.-958 C>T (rs833061) and IGFR-1 g.99181663 C>T (rs4965425). If allele T IGFR-1 or a combination of allele C VEGF-A with alleles T IGFR-1 is observed, a high risk of POAG with ineffective local antihypertensive therapy is predicted.EFFECT: invention provides new criteria for assessing risk of POAG with ineffective local antihypertensive therapy in Russian natives of Central Black Earth Region.1 cl, 4 dwg, 2 ex |
申请公布号 |
RU2598878(C1) |
申请公布日期 |
2016.09.27 |
申请号 |
RU20150110630 |
申请日期 |
2015.03.26 |
申请人 |
Federalnoe gosudarstvennoe avtonomnoe obrazovatelnoe uchrezhdenie vysshego  |
发明人 |
Churnosov Mikhail Ivanovich;Kirilenko Mikhail Yurevich;Tikunova Evgeniya Viktorovna;Sirotina Svetlana Sergeevna;Polonikov Aleksej Valerevich |
分类号 |
G01N33/50 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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