发明名称 |
Stable crystal modifications of DOTAP chloride |
摘要 |
The invention relates to enantiomerically pure DOTAP chloride and stable crystal modifications of (2R,S)-, (2S)- and (2R)-DOTAP chloride, to a process for the preparation of these modifications, and to the use thereof as constituent for the preparation of medicaments. |
申请公布号 |
US9457087(B2) |
申请公布日期 |
2016.10.04 |
申请号 |
US201414474789 |
申请日期 |
2014.09.02 |
申请人 |
MERCK PATENT GMBH |
发明人 |
Platscher Michael;Hedinger Alfred |
分类号 |
A61K47/18;A61K9/127;C07C219/08 |
主分类号 |
A61K47/18 |
代理机构 |
Millen, White, Zelano, Branigan, P.C. |
代理人 |
Millen, White, Zelano, Branigan, P.C. |
主权项 |
1. A pharmaceutical composition comprising enantiomerically pure (2R)-DOTAP chloride and essentially free of (2S)-DOTAP chloride, and a pharmaceutically acceptable carrier. |
地址 |
Darmstadt DE |