发明名称 Stable crystal modifications of DOTAP chloride
摘要 The invention relates to enantiomerically pure DOTAP chloride and stable crystal modifications of (2R,S)-, (2S)- and (2R)-DOTAP chloride, to a process for the preparation of these modifications, and to the use thereof as constituent for the preparation of medicaments.
申请公布号 US9457087(B2) 申请公布日期 2016.10.04
申请号 US201414474789 申请日期 2014.09.02
申请人 MERCK PATENT GMBH 发明人 Platscher Michael;Hedinger Alfred
分类号 A61K47/18;A61K9/127;C07C219/08 主分类号 A61K47/18
代理机构 Millen, White, Zelano, Branigan, P.C. 代理人 Millen, White, Zelano, Branigan, P.C.
主权项 1. A pharmaceutical composition comprising enantiomerically pure (2R)-DOTAP chloride and essentially free of (2S)-DOTAP chloride, and a pharmaceutically acceptable carrier.
地址 Darmstadt DE