| 发明名称 |
Method of inhibiting vertebrate collagenase activity using peptide hydroxamic acid derivatives |
| 摘要 |
Novel peptide hydroxamic acid derivatives having useful collagenase inhibitory activity and capable of forming affinity resins for the purification of vertebrate collagenase are defined by the following structural formula: R-Pro-Leu-Gly-NHOH wherein R=H or N-protecting group or agarose.
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| 申请公布号 |
US4720486(A) |
申请公布日期 |
1988.01.19 |
| 申请号 |
US19870001265 |
申请日期 |
1987.01.07 |
| 申请人 |
MONSANTO COMPANY |
发明人 |
SPILBURG, CURTIS A.;MOORE, WILLIAM M. |
| 分类号 |
C07K5/097;(IPC1-7):A61K37/02;C08F283/00 |
主分类号 |
C07K5/097 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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