| 摘要 |
The present invention provides a cationic lipid, which allow nucleic acids to be easily introduced into cells, represented by formula (I);(wherein: R1 and R2 are, the same or different, alkenyl, etc, and
X1 and X2 are hydrogen atoms, or are combined together to form a single bond or alkylene, and
X3 is absent or is alkyl, etc,
Y is absent or anion,
a and b are, the same or different, 0 to 3, and
L3 is a single bond, etc,
R3 is alkyl, etc,
L1 and L2 are —O—, —CO—O— or —O—CO—),
a composition comprising the cationic lipid and a nucleic acid, and
a method for introducing a nucleic acid into a cell by using the composition comprising the cationic lipid and the nucleic acid, and the like.
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