Systems and methods for interior energy-activation from an exterior source

摘要

A method and a system for producing a change in a medium. The method places in a vicinity of the medium at least one energy modulation agent. The method applies an initiation energy to the medium. The initiation energy interacts with the energy modulation agent to directly or indirectly produce the change in the medium. The system includes an initiation energy source configured to apply an initiation energy to the medium to activate the energy modulation agent.

主权项

1. A method for treating a condition, disorder or disease comprising:
providing an activation energy sufficient to cause a predetermined change in a subject, wherein the activation energy is generated in-situ in said subject by application of an initiation energy which is converted in-situ to said activation energy, wherein the initiation energy is at least one member selected from the group consisting of x-rays, gamma rays, and electron beams; and prior to or simultaneously with providing the activation energy, administering to the subject at least one activatable pharmaceutical agent that is activatable in situ by the activation energy, wherein upon activation, the activated at least one activatable pharmaceutical agent effects the predetermined change in the subject, wherein said predetermined change at least one of 1) causes a change in organism activity or 2) treats the condition, disorder, or disease.