发明名称 |
DISUBSTITUTED PIPERIDINE DERIVATIVES AS BUTYRYLCHOLINESTERASE INHIBITORS FOR USE IN THE TREATMENT OF ALZHEIMER |
摘要 |
This invention relates to new inhibitors of butyrylcholinesterase with general formulas I and II, where substituents are described in patent description. Compounds can be in the form of pure enantiomers or as racemic mixtures, or in the form of pharmaceutically acceptable salts. The present invention relates to the use of these inhibitors for the treatment of Alzheimer's disease and other forms of dementia. |
申请公布号 |
WO2016151484(A1) |
申请公布日期 |
2016.09.29 |
申请号 |
WO2016IB51603 |
申请日期 |
2016.03.22 |
申请人 |
UNIVERZA V LJUBLJANI |
发明人 |
BRUS, Boris;KOŠAK, Urban;KNEZ, Damijan;COQUELLE, Nicolas;COLLETIER, Jacques-Philippe;GOBEC, Stanislav |
分类号 |
A61K31/445;A61K31/4523;A61K31/453;A61K31/4709;A61P25/28;C07D215/26;C07D277/42;C07D295/04;C07D311/10 |
主分类号 |
A61K31/445 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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