| 发明名称 |
FREMGANGSMÅDE TIL FREMSTILLING AF HYDROXYLEREDE CYCLOPENTYLPYRIMIDINFORBINDELSER |
| 摘要 |
The invention provides new processes for making and purifying hydroxylated cyclopenta[d]pyrimidine compounds, which are useful for the treatment of diseases such as cancer as AKT protein kinase inhibitors, including the compound (S)-2-(4-chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-3-(isopropylamino)propan-1-one. |
| 申请公布号 |
DK2861583(T3) |
申请公布日期 |
2016.10.03 |
| 申请号 |
DK20130725533T |
申请日期 |
2013.05.17 |
| 申请人 |
Array Biopharma, Inc.;Genentech, Inc. |
发明人 |
LANE, Jonathan W.;REMARCHUK, Travis;SHAKYA, Sagar;SPENCER, Keith L.;STENGEL, Peter J. |
| 分类号 |
C07D239/42;C07D239/70;C07D403/04 |
主分类号 |
C07D239/42 |
| 代理机构 |
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